Aug 31, 2018

Welcome to Muir Diablo Occupational Medicine's research study on the treatment of Peyronie's disease using autologous adipose-derived stromal vascular fraction (ADSVF) combined with low-intensity shock wave therapy (LI-SWT). This groundbreaking approach has shown promising results in the management of Peyronie's disease, providing patients with improved outcomes and enhanced quality of life.

The Need for Innovative Treatment Options

Peyronie's disease is a condition characterized by the development of fibrous scar tissue, or plaques, within the penis. These plaques can cause penile deformity, curvature, pain, and difficulties in sexual intercourse. While the exact cause of Peyronie's disease is still not fully understood, it is believed to be related to trauma or injury to the penis.

Traditional treatment options for Peyronie's disease include medication, such as collagenase injections, and invasive surgical procedures, such as penile plication or grafting. However, these approaches may have limitations in terms of effectiveness, risks, and recovery time.

The Potential of Autologous Adipose Derived Stromal Vascular Fraction

Autologous adipose-derived stromal vascular fraction (ADSVF) therapy is an innovative regenerative medicine approach that utilizes the body's own fat tissue to extract a concentrated mixture of stem cells, growth factors, and other regenerative components. These adipose-derived cells have been shown to possess immense potential for tissue repair and regeneration.

Recent studies have demonstrated the efficacy of ADSVF in various medical applications, including the treatment of Peyronie's disease. The unique regenerative properties of the ADSVF make it a promising alternative to traditional treatment options, offering patients a non-invasive and potentially less risky approach with potentially superior outcomes.

The Role of Low-Intensity Shock Wave Therapy

In combination with ADSVF therapy, low-intensity shock wave therapy (LI-SWT) is utilized to further enhance the regenerative effects and promote penile tissue remodeling. LI-SWT involves the application of gentle shock waves to targeted areas of the penis, stimulating the release of growth factors, improving blood flow, and reducing scar tissue formation.

LI-SWT has been extensively studied for its ability to improve erectile function and promote tissue repair in various urological conditions, including Peyronie's disease. When combined with ADSVF therapy, LI-SWT has shown even more promising results, potentially accelerating the healing process and enhancing the overall treatment outcomes.

The Procedure and Treatment Outcomes

The autologous adipose-derived stromal vascular fraction combined with low-intensity shock wave therapy treatment for Peyronie's disease is a minimally invasive procedure that is performed on an outpatient basis.

During the procedure, a small amount of subcutaneous fat is harvested from the patient's own body, typically from the abdomen or thighs, using a gentle liposuction technique. The extracted fat is then processed to obtain the concentrated ADSVF, which is rich in regenerative cells.

Following the ADSVF extraction, the patient undergoes the low-intensity shock wave therapy session. The LI-SWT device emits targeted shock waves, applied to the regions of the penis affected by the plaques. The therapy session typically takes about 20-30 minutes, and multiple sessions may be required for optimal results.

Preliminary clinical studies have shown promising outcomes with this combined treatment approach for Peyronie's disease. Patients have reported improvements in penile curvature, reduction in pain, and enhanced erectile function. However, it's important to note that individual results may vary, and consultation with a qualified healthcare professional is essential to determine the appropriateness of this treatment for each patient.


At Muir Diablo Occupational Medicine, we are dedicated to advancing medical knowledge and providing innovative treatment options for our patients. Our research study on the use of autologous adipose-derived stromal vascular fraction combined with low-intensity shock wave therapy for Peyronie's disease represents our commitment to improving the quality of life of individuals affected by this condition.

If you or a loved one is living with Peyronie's disease and interested in exploring alternative treatment options, we encourage you to contact our experienced medical team. We will provide a comprehensive evaluation and discuss the potential benefits and risks of ADSVF combined with LI-SWT therapy, tailoring the treatment plan to your unique needs.

Don't let Peyronie's disease limit your life. Take the first step towards a better future by reaching out to Muir Diablo Occupational Medicine today.

Gail McCabe
This study by Muir Diablo Occupational Medicine is revolutionizing the treatment of Peyronie's disease! Combining autologous adipose-derived stromal vascular fraction (ADSVF) with low-intensity shock wave therapy (LI-SWT) has yielded impressive results. It's incredible to see how this groundbreaking approach is providing improved outcomes and a better quality of life for patients. Kudos to the researchers for their dedication in finding innovative solutions to help those with Peyronie's disease.
Nov 11, 2023